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24.2% weight loss at 48 weeks This figure from the NEJM 2023 Phase 2 trial is the most-cited data point for Retatrutide
Chen Q, Xie C, Tang K, Luo M, Zhang Z, Jin Y
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however, details on the studies are limited and are not overly informative
The up-regulated GDF15, in turn, enables AMPK to achieve full activation under metformin treatment [39]
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