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Following ischemic injury, the copper concentration in the heart gradually decreases and is positively associated with HIF-1-mediated angiogenesis and the expression of angiogenesis and glycolysis-associated genes (48)

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10,11,13 Such effects of GIP RAs and dual agonists are still under investigation

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Mitochondrial -oxidation of VPA involves its transport within 2 the mitochondrial matrix, using the same pathway as do long-chain fatty acids

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