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14.2 Monotherapy Use of MOUNJARO in Adult Patients with Type 2 Diabetes Mellitus SPL UNCLASSIFIED SECTION SURPASS-1 (NCT03954834) was a 40-week double-blind trial that randomized 478 adult patients with type 2 diabetes mellitus with inadequate glycemic control with diet and exercise to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg, or placebo once weekly

This means that while mild to moderate IBS may not prevent Wegovy use, severe gastrointestinal symptoms might warrant caution

But we need time to develop a strategy for making access to GLP-1 drugs affordable, McCarthy said

Given that it has two different mechanisms of action, it appears to have a more significant effect on weight and blood sugar than GLP-1 agonist drugs alone, such as semaglutide or liraglutide, which are both currently FDA-approved for sugar and weight control under different trade names

The active compound is the same regardless of how you take it, and both methods have solid evidence behind them

Helps lower blood sugar levels Berberine activates an enzyme called AMPK, your body's energy detector