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Description

Abstract Homologous recombination (HR) deficiency increases sensitivity to DNA-damaging agents that are commonly used to treat cancer 1

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PPAR are a family of nuclear transcription factors divided into different subtypes (PPAR , , and /) which have a large variety of effects on energy homeostasis and metabolism regulation

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In a recent double-blind randomized controlled trial, supplementation of A. muciniphilia for three months in obese participants demonstrated improved insulin sensitivity (+28.627.02%, P=0.002), and reduced insulinemia (34.087.12%, P=0.006) compared to placebo [9]. These effect sizes are not only statistically significant, they are also clinically significant and quite impressive for just administration of a single ingredient. This was a proof of concept study and we will update this page as more human literature is published investigating the metabolic effects of A. muciniphilia supplementation

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Pickart detailed that GHK-Cu can [5]: Reduce deep wrinkles and fine lines Tighten skin Improve skin density and elasticity Reverse the thinning of aged skin Protect skin cells from UV radiation Improve overall skin appearance Due to its properties, GHK-Cu is frequently included in cosmetic products, including anti-aging face creams [1]

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