Oxidative stress in liver pathophysiology and disease
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GSH exhibits multiple antioxidant actions, involving direct conjugation with free radicals such as ROS and reactive nitrogen species 46 and enzyme-mediated neutralization of free radicals, including GSH peroxidase (GPx), which detoxifies peroxides with GSH acting as an electron donor 47
Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update
J Cereb Blood Flow Metab 30(11):18471859 Bauer AT, Brgers HF, Rabie T, Marti HH (2010) Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement