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Health science reports , 7 (2), e1864.

se elimina principalmente por metabolismo proteoltico y excrecin urinaria

Generally safe to combine, but monitor skin closely for any unexpected changes

This was not the original purpose of these medications but a side effect that many have used for this benefit

Patients with diabetes should be monitored for potential worsening of diabetic retinopathy, particularly if blood glucose control improves rapidly, and doses of concomitant insulin or sulfonylureas may need adjustment to prevent hypoglycaemia