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B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month

[Melatonin: from hormone to drug?] [PMID: 8977921] Laboratory literature summary: [Melatonin: from hormone to drug?]

Nusko G, Schneider B, Ernst H, Wittekind C, Hahn EG (1997) Melanosis colia harmless pigmentation or a precancerous condition

There is a theoretical concern that aggressive senolytic clearance could remove this anti-tumor senescence signal, potentially accelerating tumor growth in individuals with pre-malignant cells