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These structures termed liposomes have the ability to protect Setria from both the action of hydrolytic enzymes and premature oxidation but also to promote fusion with the enterocyte cell membrane thereby increasing intracellular concentration

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This provides two key advantages: Protection from intestinal degradation the phospholipid bilayer shields the GSH molecule from GGT and digestive enzymes, allowing it to reach the bloodstream intact Cellular fusion the liposomal shell is composed of the same phospholipids that form cell membranes, enabling fusion with target cell membranes and direct intracellular delivery Additionally, sublingual absorption via the oral mucosa bypasses first-pass hepatic metabolism entirely, with the GSH entering systemic circulation directly from the mouth

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