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The fluorescence of the NAPstar and Peredox constructs was measured using excitation at 399 10 and 510 10 nm with emission at 578 15 and 619 15 nm for the TS and mCherry domains respectively

Resuspended cells were homogenized in a Dounce homogenizer for 3050 times on ice and spun at 700 g for 5 min at 4 C

Oral treatment generally requires four to six weeks before noticeable improvements occur , and compliance is essential for success

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The safety profile of combination therapy has not been evaluated in large-scale clinical trials and should be limited to supervised settings