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MK-677 can increase fasting glucose and decrease insulin sensitivity
Presented for research literature review only Dillin A et al
Urol Nephrol 2001
In contrast, in AMYRs bound to rAmy 15 or the pramlintide analogue, San385 16 , an Asn at the equivalent peptide position (N14 rAmy ) adopts an upward rotamer that is exposed to the solvent environment and forms a H-bond with the backbone of L291 ECL2 (Fig
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