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Nutrients , 11 (9), 2073

The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells

Hence the observed increase in GSH activity (total and reduced glutathione) in the magnesium treated diabetic animals may possibly be due to its effect on the enzymes gamma glutamyl transpeptidase (GGT), glutamate cysteine ligase and glutathione synthetase respectively

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