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Researchers involved in the trial explained that the death might occurred because the patient had asymptomatic coronary artery disease with rupture and occlusion

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More serious but rare gastrointestinal complications have been reported, including pancreatitis (though causality remains debated), gallbladder disease, and ileus in susceptible individuals

For example, a previous work reported that some patients with T2D did not respond to GLP-1 treatment 20