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Induction of HO-1 causes abnormal accumulation of ROS due to Fe 2+ accumulation, inducing ferroptosis
M.GiwercmanA.HwangK.et al (2023)
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Researchers classify it as a "stable gastric pentadecapeptide" because of its unusual stability in the harsh acidic environment of the stomach
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Abstract Acetaminophen (APAP) overdose is a leading cause of drug-induced liver damage, highlighting the limitations of current emergency treatments that primarily involve administering the glutathione precursor N-acetylcysteine and supportive therapy
