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This means tesofensine affects norepinephrine most potently, dopamine second, serotonin third
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TNF- damages cardiomyocyte mitochondria by inhibiting glycolysis and reducing mitochondrial adenosine triphosphate (ATP) production through promoting oxidative and nitrosative stress, which can result in compromised cardiac systolic function and unfavorable cardiac remodeling [83, 84]
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