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In a mouse model of amyotrophic lateral sclerosis (ALS), the chronic inhibition of NAAG peptidase activity delayed the onset of ALS symptoms and slowed the progress of the neuronal death
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Our work identifies SLC25A39 as an essential and regulated component of the mitochondrial GSH-import machinery
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In all the trials, TZP outperformed its comparators in HbA1c outcomes (reductions), diabetes reductions, WL, and risk of adverse cardiovascular events
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