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The median daily insulin dose at baseline was 42 units in the patients treated with JANUVIA and 45 units in the placebo-treated patients
This pharmacokinetic profile supports once-weekly dosing, allowing steady-state levels to build over the first 45 weeks of treatment
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Its dual-action mechanism targets additional metabolic pathways, potentially offering enhanced benefits for those with more challenging metabolic conditions
Rotating injection sites helps spread the medication over a larger surface area and prevents concentrating it into one spot
For laboratory researchers, these maintenance protocols provide a roadmap for how investigational compounds can be studied over time
