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What matters is the magnitude of the rise and whether it's accompanied by symptoms
Since 2022, the American Diabetes Association has updated its Standards of Care to recommend GLP1 receptor agonists as a firstline therapy for T2D 2 , eroding older and cheaper generics like metformin, which marks a momentous and fundamental change in treatment
Standard precautionary principles recommend avoiding use during pregnancy absent compelling medical necessity and informed risk-benefit assessment
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Berberine may also interact with various medications, particularly those metabolised by cytochrome P450 enzymes, so consult your GP or pharmacist before use
