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Journal reference: Chen, Bandy, et al

Semaglutide provides a longer, stronger signal at the receptor, often resulting in greater average weight loss in trials

Tirzepatide (Zepbound) Available doses: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg Starting dose: 2.5 mg weekly Titrated in 2.5 mg increments every 4 weeks Maintenance doses: 5 mg, 10 mg, or 15 mg weekly Higher doses tend to produce greater weight loss, but also increase the likelihood of gastrointestinal side effects and excessive appetite suppression

Patients frequently report this as the first noticeable improvement

2 Universidade Federal do Cear, UFC, Fortaleza, Cear, Brasil

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