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Effect of Weekly Subcutaneous Tirzepatide vs Placebo on Body Weight in Adults With Overweight or Obesity: The SURMOUNT-1 Randomized Clinical Trial, Subgroup Analysis by Age

WhatsApp video for international patients) to assess tolerance, side effects, weight trajectory Nutritional guidance emphasising adequate protein intake (target 1.2-1.6g per kg body weight) to preserve lean mass Resistance training referral/guidance to maintain muscle during weight loss Monitoring phase (quarterly) Repeat metabolic bloodwork at 3 months to assess trajectory Dose adjustment based on response and tolerance Body composition re-assessment Maintenance planning as goals are achieved Pricing what the program actually costs at SMA 2026 SMA pricing for GLP-1 weight management: Initial Weight Management Consultation: IDR 1,200,000 (approximately USD 72, SGD 110, GBP 57)

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Choose retatrutide if the research question specifically targets hepatic steatosis, fat oxidation, or the glucagon-axis contribution to energy expenditure, and if you can tolerate a thinner Phase 3 evidence base and longer titration window

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Hypoglycaemia risk is the primary safety consideration, along with potential joint swelling and carpal tunnel effects at higher doses