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Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study)

Source: STEP 1 Clinical Trial (N Engl J Med 2021)

Research Highlights Induces Substantial Weight Loss: Clinical trials consistently demonstrate robust, dose-dependent reductions in body weight

Any new compound can cause nausea, cramping, or loose stools in some people

Other forms may be more expensive or marketed as easier on the stomach, but they lack the extensive track record of monohydrate

These medications may not just be tools for losing weight, but part of ongoing management for a system that retains a memory of obesity and requires continued intervention