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Mean age at CAG was 63.1 9.7 years and median diabetes duration was 10 years (range 056)

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In summary, our transcriptome analysis further substantiates our experimental findings that METTL3 inhibition promotes PNT through coordinated suppression of RNA modification pathways and enhancement of pluripotency maintenance programs, reinforcing the crucial regulatory role of m 6 A modification in primed-to-nave transition