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That said, in published research to date, melanotan II administration has produced minor side effects such as fatigue, nausea, and yawning, and has not been associated with serious adverse events when administered to healthy subjects

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Most side effects diminish within weeks as the body adapts

Cell and Tissue Research , 377 (2), 153159

These processes include fatty acid synthesis, cholesterol biosynthesis, bile acid synthesis, steroid hormone biosynthesis, neurotransmitter synthesis, synthesis of heme, and the synthesis of many types of carbohydrate containing glycans that includes the glycolipids and glycoproteins