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GLS1 is inhibited by its product, glutamate [37]
These trials were discontinued because the clinical endpoints did not reach statistical significance when comparing ipamorelin to placebo [5]
We engineered our chimeric proteins with a rigid helical linker because previous research with albiglutide demonstrated that albumin's proximity to GLP-1 can significantly reduce its activity
Conclusion: Are Ipamorelin and CJC-1295 Worth It
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10.1007/s00592-021-01782-y 42
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