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In obese patients, acipimox can inhibit adipose tissue lipolysis by activating protein upregulated in macrophage by INF- (PUMA-G) (also known as the hydroxycarboxylic acid receptor 2 [HCA2] and GPR109a) receptors
No other single peptide addresses the ECM this comprehensively
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Feng R, Shou JW, Zhao ZX, He CY, Ma C, Huang M, et al
Patients with higher initial BMI may experience greater absolute weight loss but similar percentage reductions compared to those with lower starting weights
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