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The pivotal clinical trials for tirzepatide (SURPASS programme) did not identify diverticulitis as a specific adverse event of concern, as documented in the European Medicines Agency's European Public Assessment Report (EPAR)

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The evidence is strongest for improvements in weight, BMI, insulin resistance, waist circumference, and some androgen-related markers

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[129] A day later, however, the company announced another deal with China's Innovent Biologics to co-develop and commercialize at least three of Innovent's treatments over the next decade, in a deal which could generate up to $456 million