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Mechanical factors during injection can exacerbate local irritation
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The aging process triggers a DNA damage response and telomere shortening, which also leads to a decline in mitochondrial ATP production
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A., Montoya-Zavala, M
Hyperglycemia-induced oxidative stress and inflammation activate intrinsic and extrinsic apoptotic pathways, leading to programmed cell death of neurons and Schwann cells
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