They will also need to determine whether the apparent benefit is unique to GLP-1 receptor agonists or reflects a broader effect of improved metabolic control
Cardiovascular outcome trials, including SUSTAIN-6 and LEADER, demonstrated that GLP-1 therapy associated with meaningful reductions in major adverse cardiovascular events in high-risk populations
The broader principle is sound: weight-loss treatment should monitor strength, function and body composition, not scale weight alone, and resistance training plus adequate protein are sensible muscle-preservation strategies
FOR NUTRITIONAL DEFICIENCIES SOURCE: MedlinePlus
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