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In early Phase 2 trials, participants lost up to approximately 24% of their body weight over 48 weeks at higher doses
In the current review, five eligible studies were excluded from quantitative synthesis due to incomplete/non-extractable data
The safety profile of amycretin has so far aligned with other incretin-based therapies
The most extensively studied compounds are exenatide (Byetta [Amylin Pharmaceuticals, San Diego, CA], which has been approved by the US Food and Drug Administration [FDA] for the treatment of type 2 diabetes), liraglutide (Victoza [Novo Nordisk, Princeton, NJ], which has been submitted to the FDA for approval), sitaglitptin (Januvia [Abbott Laboratories, Abbott Park, IL], which has been approved by the FDA for type 2 diabetes), and vildagliptin (Galvus [Novo Nordisk, Princeton, NJ], which has been submitted to FDA)
This step is particularly important if you have existing medical conditions, including obesity
It happens when gas builds up in your intestines and is released through the rectum
