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Drug labels clearly warn GLP-1 users about unpleasant gastrointestinal side effects including nausea, vomiting, diarrhea, and constipation
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The GH response to secretagogues is saturable: beyond a certain point, additional GHRP-2 does not produce proportionally more GH because the pituitarys releasable pool and the receptor system are finite, and somatostatin feedback increasingly opposes release
Notably, individuals at the extremes of age, both infants and the elderly, as well as those with pre-existing comorbidities, particularly cardiopulmonary disorders, are at markedly increased risk (490)
