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Collectively, these evidence supports the hypothesis that NaIO 3 -induced ROS caused the damage to RPE cells by ferroptosis

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Sever et al., 2019), thus avoiding and directly counteracting VEGF tumorigenesis (Radeljak et al., 2004)

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Most of the copper in the liver is excreted in the bile, but less than 5% of the copper circulates in blood serum bound to ceruloplasmin and also as unbound free serum copper