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With those caveats in place, here is what the data and community sources describe at each phase

Early Changes Patients may notice improvements in skin hydration and glow within the first few sessions

Feldman, M

In vitro experiments demonstrated that the system can sustainably reduce VEGFR-2 protein levels by 75% within 72 h while inhibiting ANG-2 mRNA expression with over 80% silencing efficiency

Parallel work highlights possible impacts on keratinocytes and skin topography, where improvements in parameters such as fine lines and density were suggested

weeks 812 show significant improvements in firmness, wrinkle depth, and collagen density