tirzepatide single dose pen Zepbound (Tirzepatide) 7.5mg/0.5mL Pre-Filled Pens Injection – Apothera Zepbound® - TMates

Semaglutide is not recommended during pregnancy, and pregnancy planning should be discussed in advance

Semaglutide (aka Ozempic or Wegovy) has become ubiquitous because of established benefits in diabetes and obesity but SELECT showed that the drug should be considered in those who are obese with established atherosclerotic CV disease (ASCVD.) In March of 2024 the FDA approved a new indication for Wegovy based on the SELECT trial to reduce the risk of CV death, stroke, and heart attack in adults with cardiovascular disease and either obese or overweight My Thoughts on Semaglutide for Secondary Prevention After looking in detail at SELECT I realized that it does not apply to most patients in my practice

Maahs D, de Serna DG, Kolotkin RL, Ralston S, Sandate J, Qualls C, et al

Glucagon influences energy expenditure and fat metabolism by increasing calorie burn and mobilising stored energy

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PKA activity measurements PKA activity was measured using AKAR3 as previously described [22]