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Incretins today: multiple effects and therapeutic potential

Many patients see their pace of progress change once they reach the full therapeutic dose, though the timing and amount varies by individual

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Future studies should consider the influence of formulation and dosing, including whether prolonged-release preparations or chronotherapy aimed at circadian alignment might yield different outcomes

Ge J, Liu Z, Zhong Z, Wang L, Zhuo X, Li J, et al

I don't think we know what percentage of patients taking the drug are obese versus not obese