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Some users take higher doses up to 2000 mcg daily without reported issues
One major concern is that chronic use of GLP-1 RAs may create a supraphysiological state of GLP-1, leading to gastrointestinal upset, pancreatitis, or excessive stimulation of pancreatic activity
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Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats
This could partially be due to the high prevalence of obesity in Region Stockholm [13] and Sweden [11, 66], wherein a higher BMI has been reported to be significantly associated with a higher prescribing of GLP-1 RAs [67]
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