Gastrointestinal side effects from GLP-1 receptor agonists usually improve within 48 weeks as tolerance develops
Long-term GLP-1 use is generally well-tolerated, though side effects like nausea, vomiting, and constipation may persist or evolve
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Liraglutide injection : Still in shortage, with the manufacturer reporting two presentations available and three with limited availability
Christensen RH, Lehrskov LL, Wedell-Neergaard AS
Its now being investigated for potential longevity benefits and as a treatment for age-related macular degeneration