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doi: 10.1016/j.metabol.2022.155313 89 SteenbergeLHRogersSSungAYFanJPagliariniDJ

Unstable oxygen atoms in the body, which desperately seek for electrons and in the process, cause damage to collagen and the DNA of cells

The dose was MIC-informed: our in vitro MIC was 15.625 g/mL, and the intragastric concentration (~ 15 g/mL) was selected to achieve approximately 1MIC in the gastric lumen, prioritizing local (topical) gastric exposure over systemic delivery while minimizing vehicle load

Gupta S, Melnyk S, Kruger W (2013) Cystathionine -synthase-deficient mice thrive on a low-methionine diet

Allergic reactions: Allergic reactions including anaphylaxis have been reported with diclofenac and glucocorticoids

This seemingly minor change replacing glycines hydrogen side chain with alanines methyl group alters the peptides binding characteristics, tissue affinity, and research profile in meaningful ways