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Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia Email: [email protected] ORCID: Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Affiliation: 2 American MD Program, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Explor Cardiol

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PMID: 20225319 Kang ET, et al

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Consider earlier administration (3+ hours before bed) to allow cortisol-modulating effects to establish before sleep pressure builds

GH promotes lipolysis, particularly in visceral adipose tissue, which is metabolically distinct from subcutaneous fat in its sensitivity to GH-driven lipolysis