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13 In the SURPASS-4 trial (phase III), participants taking tirzepatide showed a much lower occurrence of composite kidney endpoint (time to first occurrence of eGFR decline of at least 40% from baseline, end-stage kidney disease, death due to kidney failure, or new onset albuminuria) compared with those who received insulin glargine (HR 0.58)

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This usually resolves quickly but frequent episodes may need medical evaluation at your primary care clinic in Georgetown TX

In the study, participants who received supervised exercise instruction maintained a weight loss of at least 10% of initial body weight one year after treatment termination compared with those who received liraglutide alone or placebo (4)

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Subcutaneous shots are administered just under the skin so they are less painful than intramuscular shots