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Extended titration Some researchers prefer a very gradual titration: increasing by 1.25 mg every 4 weeks instead of the standard 2.5 mg
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About 300600 milligrams per day in IV form has been shown to be beneficial
We chose to make all transport rates linear and adjusted them so that the measured APAP, APAP-S, APAP-G, and NAPQI-GSH concentrations in the plasma and the urine were as measured in the literature[4, 6, 11, 3032]
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