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No SAEs were reported, and none of the AEs led to premature treatment discontinuation

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Most recently, the high abundance of a delta GST, SzeaGSTd1 in Sitophilus zeamais antennae, inhibition of SzeaGSTd1 catalytic activity by capryl alcohol, along with the degradation of capryl alcohol by recombinant SzeaGSTd1 were observed [110]

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The presence of benzyl alcohol within the solution enables extended usability across multiple handling procedures by reducing the potential for microbial contamination during controlled laboratory access

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Secondary outcomes included absolute change in body weight and weight circumference from 36 to 88 weeks, the percentage of adults achieving at least a 5%, 10%, 15%, 20% or 25% weight loss from baseline to 88 weeks and the percentage of adults that maintained at least 80% of the body weight they lost during the open-label period

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