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The key values taken under consideration were R2 ( gross elasticity of the skin including viscous deformation, ratio of ability of recovery to final distension values) and R6 (portion of visco-elasticity on the elastic part of the curve, the smaller the value the higher the elasticity and the skin barrier firmness)

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P53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment [PMID: 20182617] Laboratory literature summary: p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment

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Upregulated expression of CPT1A has also been determined in breast cancer by an integrated genomic strategy based on the use of gene expression signatures of oncogenic pathway activity 20