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SGLT2i was also associated with lower rates of high-dose glucocorticoid, NSAID, colchicine, and diuretic dispensing, with rate ratios of 0.78 (95% CI 0.740.83), 0.85 (95% CI 0.800.92), 0.87 (95% CI 0.830.92), and 0.87 (95% CI 0.850.89), respectively

This implies that GLP-1MK-801 reduces body weight through effects on both energy intake and energy expenditure

You might also notice frequent burping (sometimes famously referred to as "sulfur burps" due to their distinct smell)

The indirect risk is the same as with any GLP-1: nausea and vomiting, especially during dose increases, can cause you to lose a pill before its absorbed

The intervention group followed a 16:8 intermittent fasting diet, whereas the control group received standard dietary advice

Some patients will remain at a 1mg maintenance dose or continue increasing until they reach a 2mg dose