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Others argue that the set point is remarkably persistent, especially in individuals with a long history of obesity
n = 8 mice per group for WT (left) and n = 6 mice per group for IL-6 KO (right) mice
"Gamma-glutamyltransferase and risk of cardiovascular mortality: A dose-response meta-analysis of prospective cohort studies." PLoS One
These reports can be helpful, but theyre not the same as large studies designed to answer safety questions
doi: 10.1056/NEJMp2400978 Summary Keywords GIP, GLP-1, GLP-1RA, tirzepatide, diabetes, obesity, cardiovascular disease Citation Liu QK (2024) Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
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