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Given the central role of B cells in SLE pathogenesis, modulating B cell function has emerged as a key therapeutic strategy to mitigate the autoimmune response in SLE (24)
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cureus [Internet]
3 Insulin resistance Insulin resistance (IR) is characterized by a reduced physiological response of insulin-sensitive tissues (including liver, skeletal muscle, and adipose tissue) to circulating insulin, although the insulin concentration is normal or even increased (66)
Adems de los efectos secundarios, el alto costo de los medicamentos tambin es una de las principales causas de interrupcin, segn un estudio independiente de la Asociacin Estadounidense de Diabetes
P = 0.009), plasminogen activator inhibitor-1 (12.90 [25.98, 0.18]
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