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Localized allergic signs include injection site reactions that worsen with each successive dose rather than improving over time, spreading hives (urticaria) extending well beyond the injection site, and severe swelling (angioedema) at the injection site that does not resolve within 48 hours
doi: 10.3390/IJMS25073812 28 ChenXZhaoPWangWGuoLPanQ
Amyotrophic lateral sclerosis Glial contributions to ALS progression Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive loss of motor neurons ( C9orf72 (chromosome 9 open reading frame 72), SOD1 (superoxide dismutase 1), TARDBP (TAR DNA-binding protein 43, coding for TDP43), and FUS (fused in sarcoma
is supported by NIH research grants OT2HL161847, OT2OD032581, U24TR001608 and CDC project numbers 75D301-21-P-12254 and 75D301-23-C-18264