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When to contact your GP, diabetes team, or healthcare professional: Severe or persistent nausea and vomiting preventing adequate fluid or food intake Signs of dehydration (dark urine, dizziness, reduced urination) Severe abdominal pain, particularly if accompanied by vomiting, or right upper abdominal pain with fever Symptoms of hypoglycaemia that don't resolve with usual treatment Unexplained weight loss exceeding clinical targets Changes in mood or suicidal thoughts Any concerns about medication tolerance or effectiveness The MHRA continues to monitor the safety profile of incretin medications through the Yellow Card scheme

Outcomes arent improving

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Also, its common that when a drug interaction website lists something as mild, its referring to an interaction thats purely theoretical and may or may not play out in reality

Track symptoms, adjust non-medical routines safely, and involve your care team when insomnia persists or red flags appear

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