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[7] [8] Oral semaglutide increases levothyroxine exposure, so thyroid function monitoring is recommended in patients taking both medications

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10.1074/jbc.M609554200 44 TsujiiY.NishidaT.OsugiN.FujiiY.SugimotoA.NakamatsuD.et al (2022)

As a result, rhGH supplementation is not approved for medical treatment of the pathophysiologic, age-related decline in GH/IGF secretion, despite the clinical similarities with classically defined, adult-onset GHD