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ScGrx7 is poorly susceptible to competitive inhibitors To test the catalytic mechanism in more detail, we performed inhibition studies with S -methylglutathione or L--glutamyl-L--aminobutyrylglycine (ophthalmic acid)

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Sulforaphane, an isothiocyanate derived from broccoli and broccoli sprouts, is the most potent naturally occurring inducer of Nrf2

Antioxidants 8(3):64 Weiss C, Maker HS, Lehrer GM (1980) Sensitive fluorometric assays for glutathione peroxidase and reductase

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Since macrophages are cells of the innate immunity present in all animals, and they produce the highest levels of oxidant and pro-inflammatory compounds in aged individuals, the role of the immune system in aging could be of universal application