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The inhibition of FAO by the knocking down of CPT1 and CPT2 significantly decreased the phosphorylation level of Src and the number of metastatic nodules, confirming the role of mitochondrial FAO and CPT genes in Src regulation and their significance in breast cancer metastasis
Received: Accepted: Published: DOI:
As mentioned previously, tumour/cancer cell metabolism is highly variable and is dependent on multiple factors like anatomical location, genetic factors, environmental conditions, lifestyle, pharmacological interventions, physiological conditions impacting the surrounding microenvironment, and availability of nutrients (illustrated in Fig
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