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Th17/IL-17A axis is critical for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc): SSc patients with high levels of serum IL-17A exhibit reduced lung functions and increased prevalence of PAH

This is because melanin production continues normally once glutathione levels drop

The study also showed that semaglutide lowered the risk of major heart problems, like heart attack or worsening heart failure, by 20% in people without diabetes who had cardiovascular disease, overweight, or obesity

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